MODERN ENDOCRINE-ONCOLOGY AND RADIOTERANOSTICS
Keywords:
radiotheranostics, PAT, SPECT, endocrinology, oncologyAbstract
Radiotheranostics is radionuclide therapy based on the results of molecular imaging with various radiopharmaceuticals, allowing in vivo visualization (using single photon emission tomography (SPECT) and/or positron emission tomography (PET)), and then systemically and selectively influencing the pathological metabolic processes caused by pathological process. In recent years, thanks to advances in the development of nuclear medicine (an increase in the number of cyclotrons, SPECT/CT and PET/CT in medical institutions) and, above all, radiopharmaceuticals, radiotheranostics is developing very rapidly in the world. The emergence of new radioligands based on 177Lu, 131I, 225Ac and other radioactive isotopes in the world has initiated a large number of clinical studies of radioligand therapy for neuroendocrine and chromaffin tumors, prostate cancer, etc. Radiotheranostics as a new and very promising area of nuclear medicine is perfectly integrated into modern diagnostic algorithms in the field of endocrinology and oncology. Intraoperative radionavigation methods can improve the efficiency and safety of surgical methods, external beam radiation therapy, and brachytherapy. In my opinion, the future of personalized medicine will largely be determined by the integration of radiotheranostics, multimodal imaging, intraoperative navigation and existing/new diagnostic and treatment methods in combination with applied genomic and post-genomic technologies.
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Copyright (c) 2024 Davranova Aziza Davranovna, Madadbek Jo`raboyev , Javohir Narzullayev , Sevara Sharopova , Mohichehra Nasriddinova
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