DIAGNOSIS AND INTENSIVE TREATMENT OF TYPE 2 DIABETES TO ACHIEVE THE TARGET LEVEL OF GLYCED HEMOGLOBIN AND REDUCE THE RISK OF VASCULAR COMPLICATIONS
Kalit so'zlar:
diabetes mellitus type 2, glycohemoglobin HbA1c, vascular complications, clinical inertia, Gliclazide MBAnnotatsiya
Control of type 2 diabetes mellitus (T2DM) requires multifactorial behavioral and pharmacological treatment to prevent the development or slow the progression of complications. The main characteristics of T2DM - hyperglycemia and insulin resistance in combination with oxidative stress, low-level inflammation, epigenetic changes, genetic predisposition, activation of the renin-angiotensin-aldosterone system, causing endothelial dysfunction, from the earliest stages are responsible for the metabolic environment that increases vascular risk in patients. Almost all patients with T2DM are at high and very high cardiovascular risk. The largest studies of the late 20th - early 21st centuries. demonstrated a significant reduction in intensive care complications early in the disease and a “legacy effect” with long-term historical significance of HbA1c control during their observational extensions. Reductions in HbA1c levels may also play a role in mediating the beneficial effects on cardiovascular risk observed with newer glucose-lowering drugs. The desires for glycemic control and organ-specific protection do not exclude, but complement each other. Reassessing individual glycemic goals and achieving them at regular intervals with early intensification of therapy is key to overcoming clinical inertia.
Библиографические ссылки
Отамуродов УГ угли, Абдужамбилов АН угли, Сабирова ДШ. Гипертиреоз. ScienceandEducation. 2023;4(5):134-139.
Шухратовна СД, Рустамовна РГ, Нодир Р. Изменения уровня хг в системе мать-плацента-плод прирезус несовместимой беременности. Достижения науки и образования. 2020;(10 (64)):91-93.
Хамраев X, Содиков С, Хамраева Д, Собирова Д. Клинико-функциональное состояние печени у больных с сахарным диабетом. ЖПБМ. 2018;(1 (99)):189-191
Даминов АТ, Хакбердиева В, Жаникулов С, Муродхонов С. Клинический случай первичный гипотиреоз. Educational Research in Universal Sciences. 2024;3(3 SPECIAL):131-134.
Shukhratovna SD, Suratovich OF. Морфологические особенности коры надпочечников потомства крыс в онтогенезе в условиях внутриутробного воздействия пестицидов через организм матери (обзорная статья). Journal of biomedicine and practice. 2023;8(4). Accessed January 12, 2024. https://tadqiqot.uz/index.php/biomedicine/article/view/8217
Мизамова МАК, Эшпулатова ГНК, Эшмуродова ЗНК, Салимова ДЭ. Осложнения акромегалии, связанные со здоровьем, текущие и перспективные варианты лечения. ScienceandEducation. 2023;4(4):187-195.
Нарбаев А, Джураева З, Курбонова Н, Кувондиков Г, Давранова А, Содиков С. Особенности изучения многофакторного управления сахарным диабетом 2 типа. Журнал проблемы биологии и медицины. 2017;(4 (97)):78-79.
Ибрагимов УС, Туракулов ЖТУ, Гуломов ШНУ, Салимова ДЭ. Просвещение пациентов: Гипогликемия (низкий уровень глюкозы в крови) у людей с диабетом. ScienceandEducation. 2023;4(4):226-233.
Содиков С, Каримова Н, Каримова З. Реабилитация больных пожилого возраста сахарным диабетом 2-типа. ЖПБМ. 2017;(4 (97)):105-106.
Хамидова МН, Исматова ИФ, Бердиеров ЖШ, Негматова ГШ, Даминов АТ. Сахарный диабети COVID-19. Eurasian Journal of Medical and Natural Sciences.2022;2(13):190-204.
Шухратовна СД, Кахрамонович ЮУ, Махмудович КТ. Структурные изменения сосудисто-стромального комплекса щитовидной железы при эутиреоидной и токсических формах зоба. Научный журнал. 2019;(10 (44)):67-69.
Собиржоновна КН, Саллохидинович СС, Акбаровна ОМ. Эпидемиологический Статус И Факторы Риска Сахарного Диабета На Сегодняшний День. MiastoPrzyszłości. 2023;32:212-219.
Salimova DE, Daminnov AT. A clinical case based on the experience of treating hypertension in a patient with type 2 diabetes mellitus, obesity and vitamin d deficiency. Educational Research in Universal Sciences. 2023;2(12):150-154.
Takhirovich DA. Assessment of hearing function in individuals with type 2 diabetes. American Journal of Pediatric Medicine and Health Sciences (2993-2149). 2023;1(9):124-126.
Qahramonov FA, Amirov BY, Tursunboyeva LI, Daminov AT. Autoimmuntireoiditbilankasallanganbemorlardagifunksionalbuzilishlarningdifferensionaldiagnostikasidaqalqonsimonbezzichliginianiqlash.Science and Education. 2023;4(3):82-86.
Nazira K, Siddikovna TG, Davranovna DA, Takhirovich DA, Tulkinovich OS. Cardiovascular complications in patients who have had covid on the background of diabetes mellitus 2.1. 2021;2(3):37-41.
Choriyev S, Gadoeva Z, Mardonova F, Jurakulov F, Hafizov S, Daminov AT. Changes in the thyroid gland in the long period after a new coronavirus infection.Science and Education. 2023;4(12):102-106.
Kamalov T, Bahriev N, Yuldashev U, Sabirova D. Clinical and hormonal characteristics of primary hypogonadism in preschool boys. MedFarm. 2019;10(9). doi:10.32743/2658-4093.2019.9.10.188
Daminov AT, Yuldoshev B, Murodullo I, Naimova N. Clinical case of primary hypothyroidsis. Educational Research in Universal Sciences. 2024;3(3 special):135-138.
Daminov A, Khaydarov O, Hasanova M, Abdukakhorova R. Complications of glucocorticoid therapy in patients diabetes survived COVID-19. Евразийскийжурналмедицинскихиестественныхнаук. 2023;3(4):197-200.
Takhirovich DA, Corners SJA, Shukhratovna NG, Shukhratovna SG, Zaynuddinovna MG. Course of COVID-19 in patients with diabetes mellitus. Web of Scientist: International Scientific Research Journal. 2022;3(02):73-76. doi:10.17605/OSF.IO/B6FU2
Shukhratovna NG, Erkinovna SD, Suxrobovna XM, Ikromovna AZ. Diabetes mellitus, ischemic heart disease and arterial hypertension. Pedagog. 2022;5(5):381-386.
O’g’li SOS, O’g’li RSO, Taxirovich DA. Diffuz toksik buqoq. Лучшиеинтеллектуальныеисследования. 2023;4(1):131-133.
Negmatova GS, Toshimova GT qizi, Abdiyev LS oʻgʻli, Daminov AT. Effectiveness of correction of dyslipidemia in elderly patients with type 2 diabetes mellitus. Educational Research in Universal Sciences. 2024;3(1 SPECIAL):269-274.
G.Sh N, D.e S, Oybekovma XS, Qamariddinovna XA, O’g’li BJA. Endocrine glands, structure, age features, functions. PEDAGOG.2022;5(5):341-345.
Sobirjonovna KN. Factors determining the clinical significance of depiptidyl peptidase 4 inhibitors in the treatment of patients with type 2 diabetes mellitus. World Bulletin of Public Health. 2022;8:67-72.
Daminov AT, Djabbarova D, Abduvohidova N, Furkatova D, Farxodova S, Ibragimova P. Features of bone tissue remodeling in patients with type 2 diabetes mellitus. Science and Education. 2023;4(11).
DaminovAbdurasulTakhirovich RSU. Features of the clinic, rehabilitation, treatment of autoimmune thyroiditis in the conditions of the iodine-deficiency region.Published online April 12, 2023. doi:10.5281/ZENODO.7820412
Shuhratovna NG, Shukhratovna SD. Features of the course of autoimmune hepatitis in children as a variant of autoimmune polyglandular syndrome. Asia Journ of MultidimensiResear (AJMR). 2020;9(7):89. doi:10.5958/2278-4853.2020.00228.1
Erkinovna SD. Features of the Course of Diabetes Mellitus Type 2 with Arterial Hypertension. JournalNX.Published online 2020:460-461.
Negmatova GS, Xakimova GD qizi, Abdiyev LS oʻgʻli, Daminov AT. Features of the rules for insulin injection techniques in elderly and senile patients with diabetes mellitus. Educational Research in Universal Sciences. 2024;3(1 special):259-264.
Takhirovich DA, Zafarovna KM, Isroilovna IS. Features of type 1 diabetes in children who have COVID-19.American Journal of Pediatric Medicine and Health Sciences (2993-2149). 2023;1(9):121-123.
Xudoyorov S, Mirkomilova M, Burxonov U, Sayfieva G, Sheralieva N, Daminov AT. Fourniers gangrene in modern conditions. Science and Education. 2023;4(12):107-117.
Alimovna KN, Sobirjanovna KN, Abdurasul D, Tulkinovich OS. Growth hormone for the treatment of hereditary diseases in children. 10.
Negmatova .G.Sh, D.e S, Qizi MZO, Mannobovich MS, Orifjonovich MM. HERPETIC MENINGITIS. PEDAGOG. 2022;5(5):346-348.
Ahrorbek N, Myungjae L, Jungjae L, et al. Hormonal Regulation. Texa Jour of Mutl Stud. 2023;25:39-43.
Ismoilova SI. Impact of vitamin D deficiency on the risk of developing type 1 diabetes.Science and Education. 2023;4(3).
T DA, Umidbekovna UM, Muhitdinovna KN. Methodology of Using Modern Graphics Programs in Teaching Engineering Graphics. 1. Published online December 8, 2023:158-162.
Sabirjanovna KN, Takhirovich DA, Jahongir D, Najmiddin X, Samandar G, Mehrangiz X. Negative Impact of Covid-19 on the Endocrine System. American Journal of Pediatric Medicine and Health Sciences (2993-2149). 2023;1(8):148-153.
Takhirovich DA, Zafarovna KM, Isroilovna IS. Nevrologiyada endokrin o`zgarishlar.songi ilmiy tadqiqotlar nazariyasi. 2023;6(12):417-422.
Negmatova GS, Salimova DE. Qandlidiabet 2-tipning arterial gipertenziyabilanbirgalikdakechishxususiyatlarivaularnidavolashusullari. Science and Education. 2023;4(2):516-519.
Taxirovich DA, J T, O E, I A. Qandli diabet-2 tipi bor bemorlarda covid-19 kasalligini glukokortikoidlar bilan davolash dinamikasini baholash. Gospodarka i Innowacje. 2023;34:78-81.
G.Sh N, D.e S, Alisherovich BA, Erkin R is the son of S, Bektash U is the son of S. Relationship between diabetic nephropathy and cardiac disorders in patients with type 2 diabetes. Pedagog. 2022;5(5):337-340.
Daminov AT, Sadullayeva SM qizi, Ismoilova SI qizi. Samarqand viloyatida qandli diabet asoratlari uchrash chastotasi. Educational Research in Universal Sciences. 2024;3(3 SPECIAL):139-142.
Shukhratovna NG, Erkinovna SD, Oʻgʻli IBI, Qizi ADD. The role of gastrointestinal hormones in the pathology of the digestive system. Pedagog. 2022;5(6):408-412.
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